Rejuran HB
Product

Rejuran HB

Renewal and moisture, together

Procedure Information at a Glance

Quick overview of treatment time, anesthesia, recovery, and recommended interval. Key information to know before the procedure.

Recommended - 3 Sessions, 2 Weeks Apart
Recommended - 3 Sessions, 2 Weeks Apart3 sessions every 2 weeks over 12 weeks (Phase III RCT)

Recommended For

Learn whether this procedure suits your concerns. Check if it matches your situation.

Thinned Dermis and Lack of Moisture01

Thinned Dermis and Lack of Moisture Those with a thin dermis and insufficient moisture, requiring simultaneous PN+HA care.

Concern: Fine Wrinkles + Skin Texture02

Concern: Fine Wrinkles + Skin Texture Those who have both fine wrinkles and rough skin texture and wish to address them simultaneously.

Desire for hydration management lasting over 1 year03

Desire for hydration management lasting over 1 year Those who desire long-lasting hydration retention with a single session.

Why Choose This Procedure

Key benefits and expected results of this procedure.

Dermis recovered with PN

Dermis recovered with PN Salmon DNA-derived PN restores the dermal environment, leading to skin that feels replenished from within.

Moisture Network with Enhanced Retention

Moisture Network with Enhanced Retention High and low molecular weight hyaluronic acid (HA) combine to form a long-lasting moisture network, not just temporary radiance.

Improved fine wrinkles

Improved fine wrinkles Dermal replenishment and collagen signals work together to naturally smooth out fine wrinkles.

Is This Right for Me?

Accurate diagnosis requires in-person consultation with our medical team. Schedule a consultation now.

What Makes It Special

Discover what makes Ineeclinic's approach to this procedure unique.

100% Satisfaction
100% Satisfaction

3-week clinical trial with 12 subjects achieved 100% satisfaction and 95.7% effectiveness. Objectively proven effects: 10.76% skin density improvement, 8.77% elasticity improvement, 34.54% oil-moisture balance improvement

Skin Barrier Strengthening
Skin Barrier Strengthening

Not just exfoliation but skin barrier improvement product. Long-term treatment fills skin from within rather than thinning or damaging it, allowing weekly treatments

Various Treatment Combinations
Various Treatment Combinations

Can be combined with various treatments: LASER, HIFU, LDM, ACNE, BOTOX. Bacteriophage, LHA, PHA ingredients work synergistically as BOOSTER PEELING to maximize effects of other treatments

Objective Clinical Data
Objective Clinical Data

Effects proven with quantitative data: skin density (10.76% improvement), TEWL (17.29% improvement), elasticity (8.77% improvement), oil-moisture balance (34.54% improvement)

Core Principles

Learn how the procedure works and what technologies and devices are used.

Salmon DNA-Derived Polynucleotides (PN)
Salmon DNA-Derived Polynucleotides (PN)Polynucleotides extracted from salmon DNA, injected into the dermis to stimulate fibroblast proliferation and dermal ECM hydration.
Dermal Collagen Synthesis (PN)
Dermal Collagen Synthesis (PN)Dermal injection of PN promotes collagen synthesis and restores ECM water-holding capacity.

Solutions Used in This Procedure

Devices, medications, and solutions used in this procedure.

See all equipment
Rejuran HB
Rejuran HB

Important Precautions

Pre- and post-procedure precautions. Review carefully for safe and effective results.

Consultation RequiredWhen combining with laser or other treatments, decide after consultation with medical staff.
Post-Treatment Sun ProtectionAvoid strong UV exposure for 1 week after treatment and apply SPF 50+ sunscreen thoroughly when outdoors. This is essential to prevent pigmentation and delayed recovery from irritation.
Enhanced Moisturizing and Soothing CareThe skin barrier may temporarily weaken after treatment, requiring thorough moisturizing and soothing care. Avoid irritating products containing alcohol or fragrance for 1 week.
Avoid Exfoliation ProductsAvoid exfoliating cosmetics, AHA/BHA peels, and physical scrubs for 1 week after treatment. Cumulative irritation on recovering skin can cause inflammation and pigmentation.
Avoid Alcohol and Vigorous ExerciseAvoid alcohol, vigorous exercise, saunas, and high-temperature environments for 24 to 48 hours after treatment. Increased blood flow and body temperature can worsen swelling and inflammation.
Follow Recommended Treatment IntervalsPlease follow the recommended 2 to 4 week interval. Excessive repeat treatments at short intervals can cause cumulative skin burden and reduce recovery capacity.

Frequently Asked Questions

Frequently asked questions from our patients.

Pain varies by procedure type and area, but most are minimized with topical or local anesthesia. Individual differences exist; consult with medical staff for appropriate pain management.

Varies by procedure. Non-invasive treatments like toning and skin boosters allow same-day return to daily life, while fractional laser or thread lifting require a few days of downtime. Follow pre-procedure guidance from medical staff.

Varies by procedure type and individual skin condition. Regular maintenance helps prolong results. Consult medical staff for recommended treatment intervals.

Evidence-Based Practice, Backed by Research

Academic publications supporting the efficacy and safety of this procedure.

Neck Rejuvenation with Calcium Hydroxylapatite, Hyaluronic Acid Filler, and IncobotulinumtoxinA: A Case Study

Neck Rejuvenation with Calcium Hydroxylapatite, Hyaluronic Acid Filler, and IncobotulinumtoxinA: A Case Study Korean Association for Laser Dermatology and Trichology

ABCs in the Prevention of Filler-induced Ocular Complications

ABCs in the Prevention of Filler-induced Ocular Complications Korean Association for Laser Dermatology and Trichology

Non-thermal, Non-equilibrium, Indirect, Jet Plasma Treatment with Nitrogen Gas As a Therapeutic Option for Acne Vulgaris: A Case Report of Clinical Experiences

Non-thermal, Non-equilibrium, Indirect, Jet Plasma Treatment with Nitrogen Gas As a Therapeutic Option for Acne Vulgaris: A Case Report of Clinical Experiences Korean Association for Laser Dermatology and Trichology

Pre-injection ultrasound scanning for treating temporal hollowing

Pre-injection ultrasound scanning for treating temporal hollowing Journal of Cosmetic Dermatology

Retrospective Study of Horizontal Neckline Correction Using Absorbable Braided Polydioxanone Threads

Retrospective Study of Horizontal Neckline Correction Using Absorbable Braided Polydioxanone Threads Korean Association for Laser Dermatology and Trichology

Sonoanatomy of the platysmal bands: What causes the platysmal band?

Sonoanatomy of the platysmal bands: What causes the platysmal band? Surgical and Radiologic Anatomy

Current practices and perceived effectiveness of polynucleotides for treatment of facial erythema by cosmetic physicians

Current practices and perceived effectiveness of polynucleotides for treatment of facial erythema by cosmetic physicians Skin Research

Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin

Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin International Journal of Molecular Sciences

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